4-氯呋喃并[3,2-c]吡啶合成路线 （共 20 条）
反应条件
trichlorophosphate T=120°C;
参考文献
Miyazaki, Yasushi; Nakano, Masato; Sato, Hideyuki; Truesdale, Anne T.; Stuart, J. Darren; Nartey, Eldridge N.; Hightower, Kendra E.; Kane-Carson, Laurie
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 1 p. 250 - 254
反应条件
trichlorophosphate in chloroform 1.5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 34, # 3 p. 925 - 929
反应条件
1: toluene / 120 °C 2: I2 / 1,2-dichloro-benzene / 170 °C 3: 84 percent / POCl3 / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 1 p. 250 - 254
反应条件
1: NaN3 / dioxane; H2O / 5 °C 2: CH2Cl2; diphenyl ether / Heating 3: 82 percent / POCl3 / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156
反应条件
1: SOCl2, DMF / CHCl3 / Heating 2: NaN3 / dioxane; H2O / 5 °C 3: CH2Cl2; diphenyl ether / Heating 4: 82 percent / POCl3 / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156
反应条件
1: 78 percent / piperidine; pyridine / 100 °C 2: 68 percent / DPPA; Et3N / tetrahydrofuran / 20 °C 3: toluene / 120 °C 4: I2 / 1,2-dichloro-benzene / 170 °C 5: 84 percent / POCl3 / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 1 p. 250 - 254
反应条件
1: I2 / 1,2-dichloro-benzene / 170 °C 2: 84 percent / POCl3 / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 1 p. 250 - 254
反应条件
1: Et3N 2: H2SO4 3: POCl3 View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 1727 - 1730
反应条件
1: H2SO4 2: POCl3 View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 1727 - 1730
反应条件
sodium hydroxide; bromine in methanol; tetrachloromethane
参考文献
Betschmann, Patrick; Burchat, Andrew F.; Calderwood, David J.; Curtin, Michael L.; Davidsen, Steven K.; Davis, Heather M.; Frey, Robin R.; Heyman, Howard R.; Hirst, Gavin C.; Hrnciar, Peter; Michaelides, Michael R.; Muckey, Melanie A.; Rafferty, Paul; Wada, Carol K.
Patent: US2005/26944 A1, 2005 ;
