您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
312708-98-8
合成路线
（共 10 条）
629-05-0
1-辛炔
+
3058-39-7
4-碘氰基苯
→
反应条件
312708-98-8
反应条件
tetra-n-butylammonium acetate; palladium diacetate in N,N-dimethyl-formamide T=20°C; Sonogashira coupling; Inert atmosphere;
参考文献
Foss Jr., Frank W.; Mathews, Thomas P.; Kharel, Yugesh; Kennedy, Perry C.; Snyder, Ashley H.; Davis, Michael D.; Lynch, Kevin R.; Macdonald, Timothy L.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 16 p. 6123 - 6136
623-03-0
对氯苯甲腈
+
15719-55-8
→
反应条件
312708-98-8
反应条件
(4R,5R)-DIOP; palladium diacetate; copper(l) chloride in N,N-dimethyl-formamide T=20 - 120°C; Sila-Sonogashira cross-coupling reaction;
参考文献
Nishihara, Yasushi; Inoue, Eiji; Noyori, Shintaro; Ogawa, Daisuke; Okada, Yoshiaki; Iwasaki, Masayuki; Takagi, Kentaro
Tetrahedron, 2012 , vol. 68, # 24 p. 4869 - 4881
623-03-0
对氯苯甲腈
+
629-05-0
1-辛炔
→
反应条件
312708-98-8
反应条件
tri-tert-butyl phosphine; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=150°C; Sonogashira coupling; 0.166667 h; microwave irradiation;
参考文献
Huang, He; Liu, Hong; Jiang, Hualiang; Chen, Kaixian
Journal of Organic Chemistry, 2008 , vol. 73, # 15 p. 6037 - 6040
629-05-0
1-辛炔
→
反应条件
312708-98-8
反应条件
1: anhydrous 1-octyne With n-butyllithium; tri-isopropoxy-borane in ethylene glycol dimethyl ether; hexane T=-78 - 20°C; 3.5 h; 2: para-bromobenzonitrile With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; ethylene glycol dimethyl ether 16 h; Heating;
参考文献
Colobert, Francoise; Castanet, Anne-Sophie; Abillard, Olivier
European Journal of Organic Chemistry, 2005 , # 15 p. 3334 - 3341
→
反应条件
312708-98-8
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; ethylene glycol dimethyl ether; hexane T=80°C; Arylation; Suzuki-Miyaura cross-coupling reaction; 5 h;
参考文献
Castanet, Anne-Sophie; Colobert, Francoise; Schlama, Thierry
Organic Letters, 2000 , vol. 2, # 23 p. 3559 - 3561
629-05-0
1-辛炔
+
36800-95-0
→
反应条件
312708-98-8
反应条件
potassium phosphate; palladium (II) trifluoroacetate; 1-dicyclohexylphosphino-2-(di-tert-butylphosphinoethyl)ferrocene in tert-butyl alcohol T=85°C; Sonogashira coupling; 7 h; Inert atmosphere;
参考文献
R'kyek, Omar; Halland, Nis; Lindenschmidt, Andreas; Alonso, Jorge; Lindemann, Peter; Urmann, Matthias; Nazare, Marc
Chemistry - A European Journal, 2010 , vol. 16, # 33 p. 9986 - 9989
15719-55-8
+
3058-39-7
4-碘氰基苯
→
反应条件
312708-98-8
反应条件
KOC(O)Ph; triphenylphosphine; copper(l) chloride in 1,3-dimethyl-imidazolidin-2-one T=120°C; Sila-Sonogashira-Hagihara cross-coupling reaction; 12 h; Inert atmosphere;
参考文献
Ihara, Hideki; Ueda, Akinori; Suginome, Michinori
Chemistry Letters, 2011 , vol. 40, # 9 p. 972 - 974
→
反应条件
312708-98-8
反应条件
cesium fluoride; SIDip*HCl; tris(dibenzylideneacetone)dipalladium (0) in 1,4-dioxane; ethylene glycol dimethyl ether Suzuki-Miyaura coupling; 3 h; Heating; Product distribution; Further Variations:CatalystsReagentsSolvents;
参考文献
Torres, Gloria Hernandez; Choppin, Sabine; Colobert, Francoise
European Journal of Organic Chemistry, 2006 , # 6 p. 1450 - 1454
21433-45-4
→
反应条件
312708-98-8
反应条件
1: 1,2-dimethoxy-ethane; tetrahydrofuran; hexane / 2.5 h / -78 - 20 °C 2: 79 percent / Pd(PPh3)4 / 1,2-dimethoxy-ethane; tetrahydrofuran; hexane / 5 h / 80 °C View Scheme
参考文献
Castanet, Anne-Sophie; Colobert, Francoise; Schlama, Thierry
Organic Letters, 2000 , vol. 2, # 23 p. 3559 - 3561
→
反应条件
312708-98-8
反应条件
triphenylphosphine in tetrahydrofuran T=70°C; Negishi Coupling; 24 h; Inert atmosphereGreen chemistry; Catalytic behavior;
参考文献
Wu, Wei-Yi; Lin, Tze-Chiao; Takahashi, Tamotsu; Tsai, Fu-Yu; Mou, Chung-Yuan
ChemCatChem, 2013 , vol. 5, # 4 p. 1011 - 1019
