3,5-二氯吡嗪-2-羧酰胺合成路线 （共 3 条）
反应条件
sodium peroxodisulphate T=23 - 90°C; Minisci Aromatic Substitution; Inert atmosphere;
参考文献
Scales, Stephanie; Johnson, Sarah; Hu, Qiyue; Do, Quyen-Quyen; Richardson, Paul; Wang, Fen; Braganza, John; Ren, Shijian; Wan, Yadong; Zheng, Baojiang; Faizi, Darius; McAlpine, Indrawan
Organic Letters, 2013 , vol. 15, # 9 p. 2156 - 2159
反应条件
1: With thionyl chloride 2: With ammonia in dichloromethane
参考文献
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1184376 A1, 2002 ;
Location in patent: Page 12 ;
反应条件
trichlorophosphate in acetonitrile T=80°C; 4 h; Inert atmosphere;
参考文献
Scales, Stephanie; Johnson, Sarah; Hu, Qiyue; Do, Quyen-Quyen; Richardson, Paul; Wang, Fen; Braganza, John; Ren, Shijian; Wan, Yadong; Zheng, Baojiang; Faizi, Darius; McAlpine, Indrawan
Organic Letters, 2013 , vol. 15, # 9 p. 2156 - 2159
