2-甲基-2,3-二氢-1H-茚-2-胺合成路线 （共 5 条）
反应条件
1: With sodium hydroxide in methanol; water T=70°C; 2 h; 2: With hydrogenchloride in water
参考文献
Beattie, David; Beer, David; Bradley, Michelle E.; Bruce, Ian; Charlton, Steven J.; Cuenoud, Bernard M.; Fairhurst, Robin A.; Farr, David; Fozard, John R.; Janus, Diana; Rosethorne, Elizabeth M.; Sandham, David A.; Sykes, David A.; Trifilieff, Alexandre; Turner, Katharine L.; Wissler, Elke
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6280 - 6285
反应条件
3-cyanobenzylnitrile; 1,2,4-(Ph)3-3,5,6-(H)3-benzene; ammonia in water; acetonitrile T=20°C; Irradiation;
参考文献
Yasuda, Masahide; Kojima, Ryuji; Tsutsui, Hiroshi; Utsunomiya, Daigo; Ishii, Kazuaki; Jinnouchi, Koutaro; Shiragami, Tsutomu
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7618 - 7624
反应条件
1: potassium hexacyanoferrate(III); ammonia / water / 10 h / 80 °C / |Inert atmosphere 2: tetrahydrofuran / 18 h / 25 °C 3: hydrogen; 10 Pd/C; sulfuric acid; acetic acid / 18 h / 25 °C / 760.05 Torr 4: sodium hydroxide / water / 1 h / 25 °C View Scheme
参考文献
Beattie, David; Beer, David; Bradley, Michelle E.; Bruce, Ian; Charlton, Steven J.; Cuenoud, Bernard M.; Fairhurst, Robin A.; Farr, David; Fozard, John R.; Janus, Diana; Rosethorne, Elizabeth M.; Sandham, David A.; Sykes, David A.; Trifilieff, Alexandre; Turner, Katharine L.; Wissler, Elke
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6280 - 6285
反应条件
1: tetrahydrofuran / 18 h / 25 °C 2: hydrogen; 10 Pd/C; sulfuric acid; acetic acid / 18 h / 25 °C / 760.05 Torr 3: sodium hydroxide / water / 1 h / 25 °C View Scheme
参考文献
Beattie, David; Beer, David; Bradley, Michelle E.; Bruce, Ian; Charlton, Steven J.; Cuenoud, Bernard M.; Fairhurst, Robin A.; Farr, David; Fozard, John R.; Janus, Diana; Rosethorne, Elizabeth M.; Sandham, David A.; Sykes, David A.; Trifilieff, Alexandre; Turner, Katharine L.; Wissler, Elke
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6280 - 6285
反应条件
1: hydrogen; 10 Pd/C; sulfuric acid; acetic acid / 18 h / 25 °C / 760.05 Torr 2: sodium hydroxide / water / 1 h / 25 °C View Scheme
参考文献
Beattie, David; Beer, David; Bradley, Michelle E.; Bruce, Ian; Charlton, Steven J.; Cuenoud, Bernard M.; Fairhurst, Robin A.; Farr, David; Fozard, John R.; Janus, Diana; Rosethorne, Elizabeth M.; Sandham, David A.; Sykes, David A.; Trifilieff, Alexandre; Turner, Katharine L.; Wissler, Elke
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6280 - 6285
