1-[(4-溴苯基)甲基]-1,3-二氢-5-(羟基甲基)-2H-咪唑-2-硫酮合成路线 （共 2 条）
反应条件
1: 4-bromo-aniline With hydrogenchloride in acetonitrile 0.05 h; Cooling with ice; 2: 1.3-dihydroxypropan-2-one; potassium thioacyanate in propionic acid; acetonitrile T=70°C; 2 h;
参考文献
Wang, Kai; Xu, Wenwei; Zhang, Wei; Mo, Mingguang; Wang, Yiping; Shen, Jianhua
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 10 p. 2897 - 2901
反应条件
acetic acid in water; acetonitrile T=55°C; Marckwald imidazole synthesis; 18 h; Product distribution; Further Variations:Solvents;
参考文献
Maligres, Peter E.; Waters, Marjorie S.; Weissman, Steven A.; McWilliams, J. Christopher; Lewis, Stephanie; Cowen, Jennifer; Reamer, Robert A.; Volante; Reider, Paul J.; Askin, David
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 2 p. 229 - 241
