4-(1,3-二氧代异吲哚啉-2-基)丁酸合成路线 （共 31 条）
反应条件
ethanol; platinum Hydrogenation;
参考文献
Journal of Organic Chemistry, , vol. 19, p. 1589,1591
反应条件
ethanol; platinum Hydrogenation;
参考文献
Journal of Organic Chemistry, , vol. 19, p. 1589,1591
反应条件
in acetonitrile Cycloaddition; 30 h; Irradiation;
参考文献
Tetrahedron, , vol. 55, # 41 p. 11997 - 12008
参考文献
Bl.Res.Coun.Israel, , vol. 7 A, p. 173,177
Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1314,1317
反应条件
sulfuric acid; water
参考文献
Chemische Berichte, , vol. 68, p. 699,701
反应条件
hydrogenchloride; [2,2']bipyridinyl; bis(1,5-cyclooctadiene)nickel (0) 1.) THF, reflux, 2.5h.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 31, # 33 p. 4783 - 4786
反应条件
1: silver oxide 2: hydrochloric acid; acetic acid; water View Scheme
参考文献
Chemicke Listy, , vol. 49, p. 1379,1381
Chem.Abstr., , p. 5681
反应条件
1: 4(1,3-dioxo-1,3-dihydroisoindol-2-yl)butyric acid With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane T=0 - 20°C; 1 h; 2: diazomethane in diethyl ether; dichloromethane T=0°C; 1.5 h; 3: With hydrogen bromide in diethyl ether; dichloromethane; water
参考文献
North Carolina State University
Patent: US2008/181923 A1, 2008 ;
Location in patent: Page/Page column 44 ;
反应条件
1: 92 percent / SOCl2 3: 48percent HBr/H2O / acetic acid View Scheme
参考文献
Michalsky et al.
Chemicke Listy, 1955 , vol. 49, p. 1379,1381
Chem.Abstr., 1956 , p. 5681
反应条件
phosphorus; bromine in tetrachloromethane Heating6-8 h;
参考文献
Journal of Organic Chemistry, , vol. 55, # 14 p. 4246 - 4255
