4-(1,3-二氧代异吲哚啉-2-基)丁酸合成路线 (共 31 条)
反应条件
1: oxalyl dichloride / dichloromethane / 8 h
2: palladium 10 on activated carbon; hydrogen; 2,6-dimethylpyridine / tetrahydrofuran / 6 h / 22 °C / 775.74 Torr
3: sodium tris(acetoxy)borohydride / dichloromethane
View Scheme
参考文献
Crawford, Jason B.; Chen, Gang; Gauthier, David; Wilson, Trevor; Carpenter, Bryon; Baird, Ian R.; McEachern, Ernie; Kaller, Alan; Harwig, Curtis; Atsma, Bem; Skerlj, Renato T.; Bridger, Gary J.
Organic Process Research and Development, 2008 , vol. 12, # 5 p. 823 - 830