1: dichloromethane / 20 - 25 °C / |Inert atmosphere 2: diisobutylaluminium hydride / dichloromethane; toluene / 1.5 h / -78 °C / |Inert atmosphere View Scheme
参考文献
West, Thomas H.; Daniels, David S. B.; Slawin, Alexandra M. Z.; Smith, Andrew D.
Journal of the American Chemical Society, 2014 , vol. 136, # 12 p. 4476 - 4479
1: With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h; 2: With hydrogenchloride; water 3 h; Dean-Stark apparatusReflux; 3: With sodium hydroxide in water pH=1;
参考文献
BIOPROJET
Patent: EP2447263 A1, 2012 ;
Location in patent: Page/Page column 27 ;
EP 2447263 A1