1: With hydrogen; Ir-chiral phosphine-oxazoline complex in dichloromethane T=20°C; P=22502.3 Torr; 0.5 h; 2: With n-butyllithium in tetrahydrofuran Further stages. Title compound not separated from byproducts.;

1: With hydrogen; Ir-chiral phosphine-oxazoline complex in dichloromethane T=20°C; P=22502.3 Torr; 0.5 h; 2: With n-butyllithium in tetrahydrofuran Further stages. Title compound not separated from byproducts.;

1: H2 / (-)-2,3-O-isopropylidene-1,4-bis(diphenylphosphino)-2,3-butanediol <(-)-DIOP> / benzene / 40 h / 20 °C / 3800 Torr 2: 1.) MeLi 2.) H3O(1+) / 1.) ether View Scheme