2-(4-羟基-3-甲氧基苯基)-1H-苯并咪唑-4-羧酸合成路线 (共 3 条)
反应条件
1: 66 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr 2: 44 percent / Cu(OAc)2 / methanol; H2O / Heating View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
1: 93 percent / Br2; aq. KOH / 3 h / 60 °C 2: 66 percent / H2 / 10percent Pd/C / methanol / 760.05 Torr 3: 44 percent / Cu(OAc)2 / methanol; H2O / Heating View Scheme
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097
反应条件
copper diacetate in methanol; water Heating;
参考文献
White; Almassy; Calvert; Curtin; Griffin; Hostomsky; Maegley; Newell; Srinivasan; Golding
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4084 - 4097