3-甲基苯并噻吩-2-羧酸合成路线 （共 16 条）
反应条件
thionyl chloride 4 h; Reflux;
参考文献
CRYSTALGENOMICS, INC.
Patent: US2011/28507 A1, 2011 ;
Location in patent: Page/Page column 24-25 ;
反应条件
1: With palladium (II) trifluoroacetate; 6-mbipy in water T=130°C; 1 h; Microwave irradiation; 2: With formic acid in water T=100°C; 1 h;
参考文献
Lindh, Jonas; Sjoeberg, Per J. R.; Larhed, Mats
Angewandte Chemie - International Edition, 2010 , vol. 49, # 42 p. 7733 - 7737
反应条件
acetic acid; silver carbonate in dimethyl sulfoxide T=120°C; 16 h;
参考文献
Lu, Pengfel; Sanchez, Carolina; Cornella, Josep; Larrosa, Igor
Organic Letters, 2009 , vol. 11, # 24 p. 5710 - 5713
反应条件
palladium (II) trifluoroacetate; silver carbonate in dimethyl sulfoxide; N,N-dimethyl-formamide T=130°C; 16 h; Inert atmosphere;
参考文献
Cornella, Josep; Lahlali, Hicham; Larrosa, Igor
Chemical Communications, 2010 , vol. 46, # 43 p. 8276 - 8278
反应条件
1: copper oxide-chromium oxide; quinoline / 170 °C 2: acetic acid; nitric acid View Scheme
参考文献
Ricci
Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 323,328
反应条件
1: copper oxide-chromium oxide; quinoline / 170 °C
2: acetic acid; aqueous hydrogen peroxide
View Scheme
参考文献
Ricci
Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 323,328
