3,3-二甲基-1-苯基-1-丁酮合成路线 （共 36 条）
反应条件
1: With titanium tetrachloride; tert-butylamine; aniline in toluene T=150°C; 22 h; 2: With water; silica gel in dichloromethane; toluene T=20°C; Further stages.;
参考文献
Kim, Hye Ryung; Yun, Jaesook
Chemical Communications, 2011 , vol. 47, # 10 p. 2943 - 2945
反应条件
1: 88 percent / Et3N / Pd<P(C6H5)3>2Cl2, CuI / acetonitrile / 1.) 0 deg C, 20 min, 2.) 25 deg C, 3 h 2: 18 percent / PI3, alumina / CH2Cl2 / 36 h View Scheme
参考文献
Casson, Sharon; Kocienski, Philip
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 9 p. 1187 - 1192
反应条件
triethyl borane; oxygen in benzene
参考文献
Song, Hyun-Ji; Lim, Che Jo; Lee, Sunggi; Kim, Sunggak
Chemical Communications, 2006 , # 27 p. 2893 - 2895
反应条件
1: 88 percent / Et3N / Pd<P(C6H5)3>2Cl2, CuI / acetonitrile / 1.) 0 deg C, 20 min, 2.) 25 deg C, 3 h 2: 18 percent / PI3, alumina / CH2Cl2 / 36 h View Scheme
参考文献
Kropp, Paul J.; Crawford, Scott D.
Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 3102 - 3112
反应条件
aluminum oxide; phosphorus(III) iodide in dichloromethane 36 h;
参考文献
Kropp, Paul J.; Crawford, Scott D.
Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 3102 - 3112
反应条件
titanium tetrachloride in dichloromethane T=-78°C;
参考文献
Chan,T.H. et al.
Tetrahedron Letters, 1977 , # 48 p. 4183 - 4186
反应条件
lithium iodide in diethyl ether T=25°C; stopped-flow ultraviolet spectroscopy; kinetics and mechanism of the conjugate addition of lithium dimethylcuprate to α,β-unsaturated ketones, substituent effect;
参考文献
House,H.O. et al.
Journal of Organic Chemistry, 1976 , vol. 41, # 19 p. 3067 - 3076
反应条件
2,4,6-trimethyl-pyridine; 2,2'-azo-bisisobutyronitrile in benzene T=85°C; 3 h; Title compound not separated from byproducts;
参考文献
Cai, Yudong; Roberts, Brian P.; Tocher, Derek A.; Barnett, Sarah A.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 17 p. 2517 - 2529
反应条件
2,4,6-trimethyl-pyridine; 2,2'-azo-bisisobutyronitrile in benzene T=85°C; 3 h; Title compound not separated from byproducts;
参考文献
Cai, Yudong; Roberts, Brian P.; Tocher, Derek A.; Barnett, Sarah A.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 17 p. 2517 - 2529
反应条件
1.1: iodine; mercuric oxide / diethyl ether / 3 h / 20 °C 1.2: 76 percent / t-BuOK / diethyl ether; tetrahydrofuran / 20 °C 2.1: AIBN; collidine / benzene / 3 h / Heating View Scheme
参考文献
Cai, Yudong; Roberts, Brian P.; Tocher, Derek A.; Barnett, Sarah A.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 17 p. 2517 - 2529
