7-氯-2,3,4,5-四氢-1H-苯并[b]氮杂卓合成路线 （共 6 条）
反应条件
methanol; magnesium 4 h;
参考文献
Kondo; Ogawa; Shinohara; Kurimura; Tanada; Kan; Yamashita; Nakamura; Hirano; Yamamura; Mori; Tominaga; Itai
Journal of Medicinal Chemistry, 2000 , vol. 43, # 23 p. 4388 - 4397
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 4 h; Heating;
参考文献
Ren, Hui; Zanger, Murray; McKee, James R.
Synthetic Communications, 2006 , vol. 36, # 3 p. 355 - 363
反应条件
1: 93 percent / hydrazine monohydrate; KOH / bis-(2-hydroxy-ethyl) ether / 6 h / Heating 2: 100 percent / Mg; methanol / 4 h View Scheme
参考文献
Kondo; Ogawa; Shinohara; Kurimura; Tanada; Kan; Yamashita; Nakamura; Hirano; Yamamura; Mori; Tominaga; Itai
Journal of Medicinal Chemistry, 2000 , vol. 43, # 23 p. 4388 - 4397
反应条件
1: 37.7 percent / sulfuryl chloride / benzene / 3 h / 20 °C 2: 88.1 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Ren, Hui; Zanger, Murray; McKee, James R.
Synthetic Communications, 2006 , vol. 36, # 3 p. 355 - 363
反应条件
1: 78.14 percent / polyphosphoric acid / 120 - 130 °C 2: 37.7 percent / sulfuryl chloride / benzene / 3 h / 20 °C 3: 88.1 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Ren, Hui; Zanger, Murray; McKee, James R.
Synthetic Communications, 2006 , vol. 36, # 3 p. 355 - 363
反应条件
1: 92.3 percent / hydroxylamine hydrochloride; pyridine / methanol / 2 h / Heating 2: 78.14 percent / polyphosphoric acid / 120 - 130 °C 3: 37.7 percent / sulfuryl chloride / benzene / 3 h / 20 °C 4: 88.1 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Ren, Hui; Zanger, Murray; McKee, James R.
Synthetic Communications, 2006 , vol. 36, # 3 p. 355 - 363
