3-(2-叔丁氧基-2-氧代乙氧基)苯甲酸合成路线 （共 5 条）
反应条件
4-(N,N-dimethlyamino)pyridine in acetonitrile
参考文献
Dixon, Seth; Ziebart, Kristin T.; He, Ze; Jeddeloh, Melissa; Yoo, Choong Leol; Wang, Xiaobing; Lehman, Alan; Lam, Kit S.; Toney, Michael D.; Kurth, Mark J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7413 - 7426
反应条件
1.1: K2CO3 / tetrahydrofuran / 1 h 1.2: tetrahydrofuran 2.1: LiOH; H2O / tetrahydrofuran / 20 °C View Scheme
参考文献
Dixon, Seth; Ziebart, Kristin T.; He, Ze; Jeddeloh, Melissa; Yoo, Choong Leol; Wang, Xiaobing; Lehman, Alan; Lam, Kit S.; Toney, Michael D.; Kurth, Mark J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7413 - 7426
反应条件
1.1: 93.7 percent / acetyl chloride / 8 h / Heating 2.1: K2CO3 / tetrahydrofuran / 1 h 2.2: tetrahydrofuran 3.1: LiOH; H2O / tetrahydrofuran / 20 °C View Scheme
参考文献
Dixon, Seth; Ziebart, Kristin T.; He, Ze; Jeddeloh, Melissa; Yoo, Choong Leol; Wang, Xiaobing; Lehman, Alan; Lam, Kit S.; Toney, Michael D.; Kurth, Mark J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7413 - 7426
反应条件
1: LiOH; H2O / tetrahydrofuran / 20 °C 2: 80 percent / DMAP / acetonitrile View Scheme
参考文献
Dixon, Seth; Ziebart, Kristin T.; He, Ze; Jeddeloh, Melissa; Yoo, Choong Leol; Wang, Xiaobing; Lehman, Alan; Lam, Kit S.; Toney, Michael D.; Kurth, Mark J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7413 - 7426
反应条件
lithium hydroxide; water in tetrahydrofuran T=20°C;
参考文献
Dixon, Seth; Ziebart, Kristin T.; He, Ze; Jeddeloh, Melissa; Yoo, Choong Leol; Wang, Xiaobing; Lehman, Alan; Lam, Kit S.; Toney, Michael D.; Kurth, Mark J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7413 - 7426
