7-氯-4(3H)-喹唑啉酮合成路线 （共 20 条）
反应条件
hydrogenchloride in water; trimethyl orthoformate
参考文献
Japan Energy Corporation
Patent: EP1229025 A1, 2002 ;
反应条件
acetic acid; diethylamine T=150°C; 2 h; Product distribution / selectivity;
参考文献
Mitsubishi Gas Chemical Company, Inc.
Patent: EP1997812 A1, 2008 ;
Location in patent: Page/Page column 8 ;
反应条件
T=130 - 190°C; 4.5 h;
参考文献
Cai, Xiong; Qian, Changgeng; Zhai, Haixiao
Patent: US2009/76022 A1, 2009 ;
Location in patent: Page/Page column 74 ;
US 20090076022 A1
参考文献
Zeneca Limited
Patent: US5952333 A1, 1999 ;
US 5952333 A
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide T=80°C; 6 h; Inert atmosphere;
参考文献
Zhou, Jing; Fu, Liangbing; Lv, Man; Liu, Jinsong; Pei, Duanqing; Ding, Ke
Synthesis, 2008 , # 24 art. no. F18308SS, p. 3974 - 3980
反应条件
1: 86 percent / Et3N / dioxane / 2 h / 20 °C 2: 16.2 percent / 186 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds, , vol. 38, # 7 p. 817 - 821
反应条件
acetic acid; diethylamine T=150°C; 2 h; Product distribution / selectivity;
参考文献
Mitsubishi Gas Chemical Company, Inc.
Patent: EP1997812 A1, 2008 ;
Location in patent: Page/Page column 8 ;
反应条件
diethylene glycol T=120°C;
参考文献
Journal of the American Chemical Society, , vol. 69, p. 184
反应条件
zinc(II) chloride T=200°C; 5 h; sealed tube;
参考文献
Organic Letters, , vol. 11, # 6 p. 1193 - 1196
反应条件
in 2-methoxy-ethanol Reflux;
参考文献
WO2012/88712 A1, ;
Page/Page column 16 ;
