Α-(对甲苯磺酰)苯乙酮合成路线 （共 66 条）
反应条件
acetic acid T=20°C; 5 h;
参考文献
Chang, Meng-Yang; Chan, Chieh-Kai; Chen, Yi-Chia
Heterocycles, 2014 , vol. 89, # 5 p. 1229 - 1236
参考文献
Schank, Kurt; Abdel Wahab, Aboel-Magd A.; Buegler, Stephan; Eigen, Peter; Jager, Juergen; Jost, Klaus
Tetrahedron, 1994 , vol. 50, # 12 p. 3721 - 3742
参考文献
Schank, Kurt; Abdel Wahab, Aboel-Magd A.; Buegler, Stephan; Eigen, Peter; Jager, Juergen; Jost, Klaus
Tetrahedron, 1994 , vol. 50, # 12 p. 3721 - 3742
反应条件
1: 98 percent / KCl; hydrogen peroxide / acetone / 6 h / 20 °C 2: 99 percent / aq. NaOH / 0.5 h / 20 °C View Scheme
参考文献
Suryakiran; Prabhakar; Srikanth Reddy; Chinni Mahesh; Rajesh; Venkateswarlu
Tetrahedron Letters, 2007 , vol. 48, # 5 p. 877 - 881
反应条件
2,2'-azo-bisisobutyronitrile in benzene T=61°C; 48 h;
参考文献
Li, Xianfeng; Chen, Jian J.; Tanner, Dennis D.
Journal of Organic Chemistry, 1996 , vol. 61, # 13 p. 4314 - 4318
反应条件
potassium carbonate in acetonitrile T=20°C;
参考文献
Suryakiran; Prabhakar; Srikanth Reddy; Chinni Mahesh; Rajesh; Venkateswarlu
Tetrahedron Letters, 2007 , vol. 48, # 5 p. 877 - 881
反应条件
1: 75 percent / sodium acetate / ethanol / 4 h / Heating
2: 65 percent / selenium dioxide / acetic acid / 50 - 60 °C
3: 65 percent / 0.25 h / Heating
View Scheme
参考文献
Padmavathi, V.; Reddy, A. V. Bhaskar; Reddy, A. Somasekhar; Reddy, D. Bhaskar
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1997 , vol. 36, # 11 p. 1062 - 1065
反应条件
1: 1-phenyl-2-tosylethanone With sodium hydride in tetrahydrofuran
T=20°C; 0.166667 h;
2: o-(trimethylsilyl)phenyl triflate; maleic acid diethyl ester With potassium fluoride; 18-crown-6 ether in tetrahydrofuran
T=65°C; Further stages.;
参考文献
Huang, Xian; Xue, Jian
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3965 - 3968
反应条件
1: 1.) K2CO3 / 1.) DMF, room temp., 1 h; 2.) DMF, room temp., 9 h
2: 1.) lithium diisopropylamide; / 1.) THF, -78 deg C, 30 min; 2.) THF, -78 deg C - room temp., overnight
3: p-toluenesulfinic acid, DBU / dioxane / 5 h / Heating
View Scheme
参考文献
Inomata, Katsuhiko; Sasaoka, Shin-ichi; Kobayashi, Toshifumi; Tanaka, Yuhji; Igarashi, Susumu; et al.
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 1767 - 1780
反应条件
acetic acid
5 h; Inert atmosphereReflux;
参考文献
Chang, Meng-Yang; Chan, Chieh-Kai; Chen, Yi-Chia
Heterocycles, 2014 , vol. 89, # 5 p. 1229 - 1236
