6-甲基-2-(1-哌啶基)-3-吡啶胺合成路线 （共 3 条）
反应条件
hydrogen; 10percent Pd/C in methanol T=20°C; P=3102.97 Torr;
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1: 76 percent / POCl3; diisopropylethylamine / 3.5 h / 90 °C 2: 85 percent / Et3N; ZnCl2 / tetrahydrofuran / 20 °C 3: 78 percent / H2 / 10percent Pd/C / methanol / 20 °C / 3102.97 Torr View Scheme
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1: 85 percent / Et3N; ZnCl2 / tetrahydrofuran / 20 °C 2: 78 percent / H2 / 10percent Pd/C / methanol / 20 °C / 3102.97 Torr View Scheme
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
