1.1: ClTi(O-i-Pr)3; i-PrMgCl / diethyl ether; hexane / 6 h / -40 °C 1.2: diethyl ether; hexane / 0.5 h / -50 - -20 °C 2.1: 55 mg / NaBH4 / methanol / 1 h / 0 °C 3.1: 97 percent / pyridine / 24 h / 20 °C 4.1: PdCl2(CH3CN)2 / tetrahydrofuran / 3 h / 20 °C 5.1: 46 mg / LiOH / methanol / 4 h / 20 °C View Scheme