N2,N2,N4,N4-四甲基-6-氯-1,3,5-三嗪-2,4-二胺合成路线 (共 8 条)
反应条件
in water; acetone a) 0 deg C, 2 h, b) RT, 18 h;
参考文献
Matsuno, Toshiyuki; Kato, Masanobu; Tsuchida, Yoshio; Takahashi, Masayuki; Yaguchi, Sin-Ichi; Terada, Sumio
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 2 p. 291 - 296
反应条件
sodium hydroxide in acetone T=20 - 50°C; 1.5 h;
参考文献
Baliani, Alessandro; Bueno, Gorka Jimenez; Stewart, Mhairi L.; Yardley, Vanessa; Brun, Reto; Barrett, Michael P.; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 17 p. 5570 - 5579
反应条件
sodium hydroxide; acetone
参考文献
Kaiser et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 2984
反应条件
in acetonitrile 0.5 h; Heating;
参考文献
Harris, Roger L. N.
Australian Journal of Chemistry, 1981 , vol. 34, # 3 p. 623 - 634
反应条件
barium dihydroxide; triethylamine T=60°C; 17 h;
参考文献
Sanders; Ames
Tetrahedron Letters, 1985 , vol. 26, # 43 p. 5247 - 5250
参考文献
Dovlatyan, V. V.; Eliazyan, K. A.; Pivazyan, V. A.; Akopyan, A. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 5 p. 550 - 552
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , # 5 p. 657 - 659
反应条件
in diethyl ether T=25°C; 48 h;
参考文献
Rushton, Philip; Stevens, Malcolm F. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1533 - 1540
反应条件
sodium hydride in N,N-dimethyl-formamide
T=130°C; 18 h; Yield given;
参考文献
Simmonds, Richard J.; Stevens, Malcolm F. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 8 p. 1821 - 1826