甲基3-(1H-咪唑-4-基)丙酸酯盐酸盐合成路线 （共 21 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=3620.13 Torr; 24 h;
参考文献
Agelis, George; Resvani, Amalia; Matsoukas, Minos-Timotheos; Tselios, Theodore; Kelaidonis, Konstantinos; Kalavrizioti, Dimitra; Vlahakos, Demetrios; Matsoukas, John
Amino Acids, 2011 , vol. 40, # 2 p. 411 - 420
反应条件
sodium chloride in methanol; dichloromethane
参考文献
Bridger, Gary; Kaller, Al; Harwig, Curtis; Skerlj, Renato; Bogucki, David; Wilson, Trevor R.; Crawford, Jason; McEachern, Ernest J.; Atsma, Bem; Nan, Siqiao; Zhou, Yuanxi; Schols, Dominique; Smith, Christopher D.; Di Fluri, Maria R.
Patent: US2004/19058 A1, 2004 ;
US 20040019058 A1
反应条件
hydrogen; triethylamine; palladium on activated charcoal in methanol T=20°C; 24 h; atmospheric pressure;
参考文献
Gupta, Preeti; Hameed, Shahul; Jain, Rahul
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 9 p. 805 - 814
反应条件
sulfuric acid 15 h; Heating / reflux;
参考文献
Bridger, Gary; Skerlj, Renato; Kaller, Ai; Harwig, Curtis; Bogucki, David; Wilson, Trevor R.; Crawford, Jason; McEachern, Ernest J.; Atsma, Bem; Nan, Siqiao; Zhou, Yuanxi; Schols, Dominique; Smith, Christopher Dennis; Di Fluri, Maria Rosaria
Patent: US2003/220341 A1, 2003 ;
Location in patent: Page/Page column 36-37 ;
US 20030220341 A1
反应条件
palladium in methanol
参考文献
US5968965 A1, ;
US 5968965 A
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 24 h;
参考文献
Dubey, Ravi Kant; Kumar, Neeraj; Jain, Rahul
Synthetic Communications, 2012 , vol. 42, # 15 p. 2207 - 2216
反应条件
1: 98 percent / HCl / 20 °C 2: 93 percent / H2; Et3N / Pd/C / methanol / 24 h / 20 °C / atmospheric pressure View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 39, # 9 p. 805 - 814
反应条件
hydrogen; palladium on activated charcoal in ethanol Ambient temperature; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 10 p. 1139 - 1148
反应条件
1: diethyl ether / 0.17 h / 0 °C 2: H2 / 5percent Pd/C / ethanol / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 10 p. 1139 - 1148
反应条件
1: sulfuric acid; sodium sulfate / 24 h / Reflux 2: palladium 10 on activated carbon; hydrogen / methanol / 8 h / 20 °C View Scheme
参考文献
Amino Acids, , vol. 40, # 2 p. 411 - 420
