sodium hydrogencarbonate in water Yield given;

1.5 h; Ambient temperature;

in pyridine T=20°C; 16 h; Yield given. Yields of byproduct given;

1.1: pyridine / 0 - 20 °C 2.1: boron trifluoride diethyl etherate / chloroform / 0.17 h / 0 - 20 °C / Inert atmosphere 2.2: 2 h / 20 °C / Inert atmosphere 3.1: methanol; sodium methylate / 1.5 h / 20 °C / pH 9 4.1: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 20 - 50 °C 5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / Inert atmosphere 5.2: 20 °C / Inert atmosphere 6.1: hydrogenchloride; sodium cyanoborohydride / tetrahydrofuran; diethyl ether / 5 h / 0 - 20 °C / Molecular sieve 7.1: N-iodo-succinimide; silver trifluoromethanesulfonate / dichloromethane / 0.17 h / 20 °C / Inert atmosphere View Scheme