Alpha-甲基苯乙酸甲酯合成路线 （共 146 条）
反应条件
samarium diiodide; water; triethylamine in tetrahydrofuran T=20°C; 24 h; Inert atmosphere;
参考文献
Szostak, Michal; Spain, Malcolm; Procter, David J.
Chemical Communications, 2011 , vol. 47, # 37 p. 10254 - 10256
反应条件
InI3; dimethylphenylsilane in dichloromethane T=20°C; 1.66667 h; Inert atmosphere; chemoselective reaction;
参考文献
European Journal of Organic Chemistry, , # 18 p. 3382 - 3386
反应条件
Zn4(OCOCF3)6O in dichloromethane
18 h; Heating / reflux;
参考文献
Takasago International Corporation
Patent: EP1958940 A1, 2008 ;
Location in patent: Page/Page column 32 ;
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran
1.2: 2 h / 25 °C
2.1: UV-irradiation
View Scheme
参考文献
Shiraki, Saori; Natarajan, Arunkumar; Garcia-Garibay, Miguel A.
Photochemical and Photobiological Sciences, 2011 , vol. 10, # 9 p. 1480 - 1487
反应条件
1: 94.8 percent / LiAlH4 / diethyl ether / 1.17 h / Ambient temperature
2: 97.2 percent / pyridine / 22.5 h / Ambient temperature
3: 0.1 M phosphate buffer (pH 7.0) / methanol / 2 h / 35 - 36 °C / lipase PRL-Sigma L-3126
View Scheme
参考文献
Matsumoto; Takeda; Iwata; Sakamoto; Ishida
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 6 p. 1191 - 1197
反应条件
1: 2-methyl-2-phenylpropionate, methyl ester With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 2 h;
2: chloro-trimethyl-silane in tetrahydrofuran
T=20°C; 20 h;
参考文献
Nishimoto, Yoshihiro; Ueda, Hiroki; Yasuda, Makoto; Baba, Akio
Angewandte Chemie - International Edition, 2012 , vol. 51, # 32 p. 8073 - 8076
