Alpha-甲基苯乙酸甲酯合成路线 （共 146 条）
反应条件
iodine T=23°C; 24 h;
参考文献
Yamauchi, Takayoshi; Hattori, Kaneaki; Nakao, Kenji; Tamaki, Kentaro
Journal of Organic Chemistry, 1988 , vol. 53, # 20 p. 4858 - 4859
反应条件
1: para-toluenesulfonic acid; Ph2PyP / Pd(OAc)2 / 4 h / 60 °C / 30002.4 Torr 2: H2 / Rh(acac)(CO)2; 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenylphosphaadamantane / toluene / 70 h / 100 °C / 3750.3 Torr View Scheme
参考文献
Clarke, Matthew L.
Tetrahedron Letters, 2004 , vol. 45, # 21 p. 4043 - 4045
反应条件
thallium(III) nitrate
参考文献
Moriarty, Robert M.; Vaid, Radhe K.; Duncan, Michael P.; Vaid, Beena K.
Tetrahedron Letters, 1987 , vol. 28, # 25 p. 2845 - 2848
反应条件
p-benozquinone; palladium(II) 2,4-pentanedionate; toluene-4-sulfonic acid; (S)-MeO-BIPHEP T=50°C; P=262521 Torr; 20 h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Nefkens, Sylvia C. A.; Sperrle, Martin; Consiglio, Giambattista
Angewandte Chemie, 1993 , vol. 105, # 12 p. 1837 - 1838
反应条件
3-chloro-benzenecarboperoxoic acid in methanol T=25°C; 5 h;
参考文献
Uemura, Sakae; Ohe, Kouichi; Yamauchi, Takayoshi; Mizutaki, Shoichi; Tamaki, Kentaro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 4 p. 907 - 910
反应条件
peracetic acid; sodium acetate in methanol T=20°C; 18 h;
参考文献
Higgins, Stanley D.; Thomas, C. Barry
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 7 p. 1483 - 1488
反应条件
in tetrahydrofuran T=-78 - 25°C; 2 h; Yield given;
参考文献
Gong, Leyi; Leung-Toung, Regis; Tidwell, Thomas T.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3634 - 3639
反应条件
sodium tetrahydroborate; triethyl borane; diphenyl{(1S,2R,3S,4R)-3-hydroxymethylbicyclo[2.2.1]heptan-2-yl}tin iodide in ethanol; hexane 19 h; Ambient temperature;
参考文献
Beddoes, Roy; Pratt, Robert M.; Thomas, Eric J.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 4 p. 717 - 726
反应条件
1: 62 percent / triphenyl phosphine / CH2Cl2 / 48 h / Heating 2: 77 percent / H2 / 5 percent Pd/C / methanol / 16 h / 20 °C View Scheme
参考文献
Patil; Wadia
Synthetic Communications, 2002 , vol. 32, # 18 p. 2821 - 2827
参考文献
McElvain; Stevens
Journal of the American Chemical Society, 1946 , vol. 68, p. 1917,1921
