Alpha-甲基苯乙酸甲酯合成路线 (共 146 条)
反应条件
water; iodine; sodium nitrite T=20 - 70°C; chemoselective reaction;
参考文献
Kiran; Ikeda, Reiko; Sakai, Norio; Konakahara, Takeo
Synthesis, 2010 , # 2 art. no. F16609SS, p. 276 - 282
反应条件
trifluoroacetic acid in benzene T=80°C; 28 h;
参考文献
Novokreshchennykh, V. D.; Lukashova, E. A.; Mochalov, S. S.; Shabarov, Yu. S.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2022 - 2027
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2315 - 2321
反应条件
iodine T=23°C; 24 h;
参考文献
Yamauchi, Takayoshi; Hattori, Kaneaki; Nakao, Kenji; Tamaki, Kentaro
Journal of Organic Chemistry, 1988 , vol. 53, # 20 p. 4858 - 4859
反应条件
hydrogenchloride; triphenylphosphine; Pd(OAc)2 immobilized on montmorillonite T=125°C; P=31028.9 Torr; 24 h; Yield given;
参考文献
Zuniga, Cesar; Sierra, Diego; Oyarzo, Juan; Klahn, A. Hugo
Journal of the Chilean Chemical Society, 2012 , vol. 57, # 2 p. 1101 - 1103,3
反应条件
1: 2,2,5-trimethyl-5-phenyl-1,3-dioxane-4,6-dione With scandium tris(trifluoromethanesulfonate) in chloroform-d1 T=50°C; 48 h; Inert atmosphere; 2: methanol Inert atmosphere;
参考文献
Fillion, Eric; Fishlock, Dan
Tetrahedron, 2009 , vol. 65, # 33 p. 6682 - 6695
反应条件
1: methylphenylketene methyl trimethylsilyl acetal; phenylacetylene With gallium(III) bromide in dichloromethane T=20°C; 2 h; Inert atmosphere; 2: iodobenzene With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; sodium t-butanolate in dichloromethane; N,N-dimethyl-formamide T=100°C; 48 h; Inert atmosphere; stereoselective reaction;
参考文献
Nishimoto, Yoshihiro; Ueda, Hiroki; Yasuda, Makoto; Baba, Akio
Chemistry - A European Journal, 2011 , vol. 17, # 40 p. 11135 - 11138
反应条件
potassium hydroxide 2 h; Ambient temperature;
参考文献
Althoff, Wolfgang; Tinapp, Peter
Archiv der Pharmazie (Weinheim, Germany), 1982 , vol. 315, # 4 p. 289 - 294
反应条件
3-chloro-benzenecarboperoxoic acid 2 h; Heating;
参考文献
Uemura, Sakae; Ohe, Kouichi; Yamauchi, Takayoshi; Mizutaki, Shoichi; Tamaki, Kentaro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 4 p. 907 - 910
反应条件
[2,2']bipyridinyl; tetrabutylammomium bromide; niobium bromide in N,N-dimethyl-formamide 5 h; electrochemical process;
参考文献
Conan, Annie; Sibille, Soline; d'Incan, Esther; Perichon, Jacques
Journal of the Chemical Society, Chemical Communications, 1990 , # l p. 48 - 49
反应条件
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=20°C; Yield given;
参考文献
Gompper, Rudolf; Vogt, Hans-Hubert
Chemische Berichte, 1981 , vol. 114, # 8 p. 2866 - 2883