(3R,4R)-3,4-Dihydro-2H-pyran-3,4-diyl diacetate合成路线 （共 22 条）
反应条件
1: methanol; sodium methylate / 4 h / 20 °C
2: dipyridinium dichromate; acetic acid / ethyl acetate / 16 h / 20 °C
3: caesium carbonate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
4: Oxonereg;; C8H6O4(2-)*Cu(2+) / toluene / 6 h / 60 °C / Molecular sieve; Air atmosphere
5: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane
6: toluene-4-sulfonic acid / toluene / 1 h / Reflux
View Scheme
参考文献
Matsuo, Kazumasa; Shindo, Mitsuru
Tetrahedron, 2011 , vol. 67, # 5 p. 971 - 975
反应条件
1: methanol; sodium methylate / 4 h / 20 °C
2: dipyridinium dichromate; acetic acid / ethyl acetate / 16 h / 20 °C
3: Oxonereg;; C8H6O4(2-)*Cu(2+) / toluene / 7 h / 60 °C / Molecular sieve; Air atmosphere
4: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / Reflux
View Scheme
参考文献
Matsuo, Kazumasa; Shindo, Mitsuru
Tetrahedron, 2011 , vol. 67, # 5 p. 971 - 975
