1-甲基-5-硝基-2-苯基-1H-吲哚合成路线 （共 7 条）
反应条件
1: INF55 With sodium hydride in DMF (N,N-dimethyl-formamide) T=20°C; 1 h; 2: methyl iodide in DMF (N,N-dimethyl-formamide) T=20°C; 1 h;
参考文献
ROTTAPHARM SPA
Patent: US2005/197331 A1, 2005 ;
Location in patent: Page/Page column 16 ;
反应条件
caesium acetate; triphenylphosphine; palladium diacetate in N,N-dimethyl acetamide T=125°C; 24 h;
参考文献
Lane, Benjamin S.; Brown, Meghann A.; Sames, Dalibor
Journal of the American Chemical Society, 2005 , vol. 127, # 22 p. 8050 - 8057
反应条件
1: INF55 With sodium hydride in N,N-dimethyl-formamide 0.5 h; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; 18 h;
参考文献
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
Patent: WO2008/6663 A1, 2008 ;
Location in patent: Page/Page column 12-13 ;
反应条件
(1,3-di(2,4,6-(CH3)3-C6H2)-imidazol-2-ylidene)Pd(OAc)2; acetic acid T=60°C; 24 h;
参考文献
Deprez, Nicholas R.; Kalyani, Dipannita; Krause, Andrew; Sanford, Melanie S.
Journal of the American Chemical Society, 2006 , vol. 128, # 15 p. 4972 - 4973
反应条件
1.1: NaH / dimethylformamide / 0 °C 1.2: 92 percent / dimethylformamide / 0 - 20 °C 2.1: 61 percent / cesium acetate; palladium acetate; triphenylphosphine / N,N-dimethyl-acetamide / 24 h / 125 °C View Scheme
参考文献
Lane, Benjamin S.; Sames, Dalibor
Organic Letters, 2004 , vol. 6, # 17 p. 2897 - 2900
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; acetic acid; silver(l) oxide in tetrahydrofuran; ethanol T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Liang, Zunjun; Yao, Bangben; Zhang, Yuhong
Organic Letters, 2010 , vol. 12, # 14 p. 3185 - 3187
反应条件
sulfuric acid; potassium nitrate T=5°C; 0.0833333 h;
参考文献
Eberson, Lennart; Giorgini, Elisabetta; Greci, Lucedio; Tosi, Giorgio; Rizzoli, Corrado; et al.
Gazzetta Chimica Italiana, 1993 , vol. 123, # 1 p. 45 - 52
