1-(3-乙氧基-4-甲氧基苯基)乙酮合成路线 (共 11 条)
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 1 h;
2: With diethyl chlorophosphate in tetrahydrofuran
T=-78 - 20°C; 3 h;
3: With water; lithium diisopropyl amide
Product distribution / selectivity; more than 3 stages;
参考文献
Altana Pharma AG
Patent: US2007/259868 A1, 2007 ;
Location in patent: Page/Page column 16 ;