3-(4-甲氧基苯甲酰基)丙酸合成路线 （共 71 条）
反应条件
1: Zn/HCl 2: CF3COOH, (CF3COO)2O 3: 2.) 10percent HCl / 1.) Et2O, reflux, 4 h, 2.) CH2Cl2 View Scheme
参考文献
Krohn, Karsten; Zimmermann, Gregor
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4140 - 4142
参考文献
Schwenk et al.
Journal of Organic Chemistry, 1944 , vol. 9, p. 1,5
反应条件
1: 95 percent / NH2NH2*H2O; KOH / bis-(2-hydroxy-ethyl) ether / 7 h / 130 - 195 °C 2: 87.7 percent / H3PO4; P2O5 / 3 h / 70 - 80 °C View Scheme
参考文献
Krohn, Karsten; Zimmermann, Gregor
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4140 - 4142
反应条件
1.1: hydrazine hydrate; potassium hydroxide / bis-(2-hydroxy-ethyl) ether / 1 h / Heating 1.2: 70 percent / bis-(2-hydroxy-ethyl) ether / 2 h / 180 °C 2.1: 65 percent / acetone / 10 h / Heating 3.1: LiAlH4 / diethyl ether / 8 h / Heating View Scheme
参考文献
Jefferies, Latisha R.; Cook, Silas P.
Organic Letters, 2014 , vol. 16, # 7 p. 2026 - 2029
反应条件
1: methanesulfonyl chloride, pyridine / 1 h / 0 °C 2: NH3(gas) / Ambient temperature 3: methanesulfonyl chloride / 2 h / 0 - 20 °C View Scheme
参考文献
Dillard, Robert D.; Hahn, Richard A.; McCullough, Doris; Carr, F. Patrick; Rinkema, Lynn E.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2768 - 2778
反应条件
1: chloroform; bromine 2: sodium acetate; glacial acetic acid View Scheme
参考文献
Bougault
Annales de Chimie (Cachan, France), 1908 , vol. <8> 15, p. 501
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1908 , vol. 146, p. 141 Anm.
反应条件
hydrazine carboxylic acid ester T=90°C; 3 h; Green chemistry;
参考文献
Tetrahedron Letters, , vol. 54, # 11 p. 1384 - 1388
反应条件
disodium hydrogenphosphate; sodium acetate; permanganate(VII) ion T=29.85°C; Oxidation; pH=6.5; Kinetics; Further Variations:TemperaturesReagents;
参考文献
Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, , vol. 38, # 2 p. 183 - 186
反应条件
1: With potassium hydroxide; hydrazine hydrate in 1,2-bis-(2-hydroxyethoxy)-ethane 1.5 h; Heating; 2: in 1,2-bis-(2-hydroxyethoxy)-ethane T=220°C; 4 h;
参考文献
Panda, Atulya Kumar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 2 p. 372 - 375
反应条件
1: N2H4*H2O / ethanol / 4 h / Heating 2: Br2 / acetic acid / 3 h / Heating View Scheme
参考文献
Ochiai, Koji; Takita, Satoshi; Kojima, Akihiko; Eiraku, Tomohiko; Iwase, Kazuhiko; Kishi, Tetsuya; Ohinata, Akira; Yageta, Yuichi; Yasue, Tokutaro; Adams, David R.; Kohno, Yasushi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 375 - 381
