1-甲基-1,10-菲罗啉-2(1H)-酮合成路线 （共 14 条）
反应条件
K3Fe(CN)6; sodium hydroxide in water T=45 - 60°C; 18 h;
参考文献
Boettger, Matthias; Wiegmann, Bjoern; Schaumburg, Steffen; Jones, Peter G.; Kowalsky, Wolfgang; Johannes, Hans-Hermann
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1037 - 1047
反应条件
sodium hydroxide; dimethyl sulfate; potassium hexacyanoferrate(III) in diethyl ether; water; toluene
参考文献
Basell Polyolefine GmbH
Patent: US2010/234548 A1, 2010 ;
反应条件
1: T=120°C; 1 h; 2: With water; sodium hydroxide; potassium hexacyanoferrate(III) in diethyl ether T=0°C;
参考文献
Akerboom, Sebastiaan; Van Den Elshout, Jos J. M. H.; Mutikainen, Ilpo; Siegler, Maxime A.; Fu, Wen Tian; Bouwman, Elisabeth
European Journal of Inorganic Chemistry, 2013 , # 36 p. 6137 - 6146
反应条件
potassium hexacyanoferrate(III) in water; acetonitrile T=25°C; Rate constant;
参考文献
Eggers, Friederike; Luening, Ulrich
European Journal of Organic Chemistry, 2009 , # 14 p. 2328 - 2341
反应条件
1: PCl5; POCl3 2: sodium methylate; methanol View Scheme
参考文献
Akerboom, Sebastiaan; Van Den Elshout, Jos J. M. H.; Mutikainen, Ilpo; Siegler, Maxime A.; Fu, Wen Tian; Bouwman, Elisabeth
European Journal of Inorganic Chemistry, 2013 , # 36 p. 6137 - 6146
反应条件
1: phosphorus pentachloride; trichlorophosphate / 12 h / |Reflux 2: acetamide; potassium carbonate / 1.5 h / 200 °C View Scheme
参考文献
Akerboom, Sebastiaan; Van Den Elshout, Jos J. M. H.; Mutikainen, Ilpo; Siegler, Maxime A.; Fu, Wen Tian; Bouwman, Elisabeth
European Journal of Inorganic Chemistry, 2013 , # 36 p. 6137 - 6146
反应条件
1: PCl5, POCl3 / 8 h / Heating 2: 3 h / Heating 3: K3<Fe(CN)6>, conc. NaOH / 3 h / 5 °C View Scheme
参考文献
B.R.A.H.M.S GmbH; HOSHINO, Mikio; YANO, Toshisada; YAMANAKA, Yasukazu
Patent: WO2012/124310 A1, 2012 ;
反应条件
1: PCl5, POCl3 / 8 h / Heating 2: 3 h / Heating 3: K3<Fe(CN)6>, conc. NaOH / 3 h / 5 °C 4: PCl5, POCl3 / 8 h / Heating View Scheme
参考文献
B.R.A.H.M.S GmbH; HOSHINO, Mikio; YANO, Toshisada; YAMANAKA, Yasukazu
Patent: WO2012/124310 A1, 2012 ;
反应条件
1: With phosphorus pentachloride; trichlorophosphate Inert atmosphereCooling in iceReflux; 2: With ammonia in water Alkaline conditions;
参考文献
B.R.A.H.M.S GmbH; HOSHINO, Mikio; YANO, Toshisada; YAMANAKA, Yasukazu
Patent: WO2012/124310 A1, 2012 ;
Location in patent: Page/Page column 33-34 ;
反应条件
1: With phosphorus pentabromide; phosphorus oxytribromide T=20 - 80°C; Inert atmosphere; 2: With ammonia in water Alkaline conditions;
参考文献
B.R.A.H.M.S GmbH; HOSHINO, Mikio; YANO, Toshisada; YAMANAKA, Yasukazu
Patent: WO2012/124310 A1, 2012 ;
Location in patent: Page/Page column 35-36 ;
