1,3-二丙基-7-甲基黄嘌呤合成路线 （共 4 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 12 h; Inert atmosphere;
参考文献
Liu, Gang; Reddy, P.S. Murali; Barber, Jack R.; Ng, Shi Chung; Zhou, Yuefen
Synthetic Communications, 2010 , vol. 40, # 10 p. 1418 - 1436
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; 9 h;
参考文献
Sakai, Ryosuke; Konno, Kayo; Yamamoto, Yasunori; Sanae, Fujiko; Takagi, Kenzo; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4039 - 4044
反应条件
1: 74 percent / K2CO3 / dimethylformamide / 1 h / Ambient temperature 2: 67 percent / K2CO3 / dimethylformamide / 9 h / 60 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 22 p. 4039 - 4044
反应条件
1: 85 percent / 2 N aq. NaOH / 1.5 h / Heating 2: 74 percent / K2CO3 / dimethylformamide / 1 h / Ambient temperature 3: 67 percent / K2CO3 / dimethylformamide / 9 h / 60 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 22 p. 4039 - 4044
