2-(4-甲氧基苯基)-咪唑并[1,2-a]嘧啶合成路线 (共 7 条)
反应条件
1: in ethanol T=78°C; 16 h; 2: With sodium hydroxide in dichloromethane; water
参考文献
Aginagalde, Maialen; Vara, Yosu; Arrieta, Ana; Zangi, Ronen; Cebolla, Vicente L.; Delgado-Camon, Arantzazu; Cossio, Fernando P.
Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 2776 - 2784
反应条件
potassium carbonate in chloroform 2 h; Heating;
参考文献
Liu, Zhi; Chen, Zhen-Chu; Zheng, Qin-Guo
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 5 p. 909 - 911
反应条件
1: 1-(4-methoxyphenyl)ethanone With (hydroxy(tosyloxy)iodo)benzene; 1-butylpyridinium tetrafluoroborate Heating; 2: 2-amino-pyrimidine With sodium carbonate; 1-butylpyridinium tetrafluoroborate T=20°C;
参考文献
Xie, Yuan-Yuan
Synthetic Communications, 2005 , vol. 35, # 13 p. 1741 - 1746
反应条件
sodium carbonate in poly(ethylene glycol-400) T=20°C; 0.5 h;
参考文献
Cheng, Hui-Ting; Hou, Rei-Sheu; Wang, Huey-Min; Kang, Iou-Jiun; Lin, Pei-Ying; Chena, Ling-Ching
Journal of the Chinese Chemical Society, 2009 , vol. 56, # 3 p. 632 - 635
反应条件
in acetonitrile 6 h; Heating;
参考文献
Aggarwal, Ranjana; Sumran, Garima
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 12 p. 2690 - 2695
反应条件
1: acetonitrile / Heating 2: 52 percent / acetonitrile / 6 h / Heating View Scheme
参考文献
Aggarwal, Ranjana; Sumran, Garima
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 12 p. 2690 - 2695
反应条件
1: sodium nitrite / acetic acid
2: H2 / Raney nickel
View Scheme
参考文献
Rival; Grassy; Michel
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 5 p. 1170 - 1176