3-(2-硝基乙烯基)吲哚合成路线 （共 21 条）
反应条件
1: sodium tetrahydroborate / methanol; tetrahydrofuran / 0.5 h / 20 °C 2: hydrogen; palladium 10 on activated carbon / 12 h / 40 °C 3: triethylamine / dichloromethane / 3 h / 20 °C View Scheme
参考文献
Guo, Xiaoke; Yang, Qian; Xu, Jing; Zhang, Li; Chu, Hongxi; Yu, Peng; Zhu, Yingying; Wei, Jinglian; Chen, Weilin; Zhang, Yaozhong; Zhang, Xiaojin; Sun, Haopeng; Tang, Yiqun; You, Qidong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6466 - 6476
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Guo, Xiaoke; Yang, Qian; Xu, Jing; Zhang, Li; Chu, Hongxi; Yu, Peng; Zhu, Yingying; Wei, Jinglian; Chen, Weilin; Zhang, Yaozhong; Zhang, Xiaojin; Sun, Haopeng; Tang, Yiqun; You, Qidong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6466 - 6476
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=20°C; 6 h;
参考文献
Vo, Quan V.; Trenerry, Craige; Rochfort, Simone; Wadeson, Jenny; Leyton, Carolina; Hughes, Andrew B.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 2 p. 856 - 864
反应条件
Na[HB(OMe)3] in tetrahydrofuran 0.333333 h; pH=6; Yields of byproduct given;
参考文献
Kruse, Lawrence I.; Hilbert, Eileen L.
Heterocycles, 1983 , vol. 20, # 7 p. 1373 - 1377
反应条件
silica gel in ethyl acetate 0.15 h; Irradiation;
参考文献
Chakrabarty, Manas; Basak, Ramkrishna; Ghosh, Nandita; Harigaya, Yoshihiro
Tetrahedron, 2004 , vol. 60, # 8 p. 1941 - 1949
反应条件
toluene-4-sulfonic acid in acetonitrile 5 h; Heating;
参考文献
Chakrabarty, Manas; Basak, Ramkrishna; Ghosh, Nandita; Harigaya, Yoshihiro
Tetrahedron, 2004 , vol. 60, # 8 p. 1941 - 1949
反应条件
1: LiAlH4 / tetrahydrofuran / Heating 2: 39 percent / Et3N / tetrahydrofuran / 6 h / 20 °C View Scheme
参考文献
Ates-Alagoz; Buyukbingol; Buyukbingol, Erdem
Pharmazie, 2005 , vol. 60, # 9 p. 643 - 647
反应条件
1,4-diaza-bicyclo[2.2.2]octane in benzene 16 h; Heating; Title compound not separated from byproducts;
参考文献
Yan, Ming-Chung; Tu, Zhijay; Lin, Chunchi; Ko, Shengkai; Hsu, Jianming; Yao, Ching-Fa
Journal of Organic Chemistry, 2004 , vol. 69, # 5 p. 1565 - 1570
反应条件
aluminium trichloride in toluene
2 h; Heating; Title compound not separated from byproducts;
参考文献
Anisimova; Berkova; Ladygin; Berestovitskaya
Russian Journal of Organic Chemistry, 2006 , vol. 42, # 8 p. 1246 - 1247
反应条件
hydroquinone
T=130 - 140°C; 25 h; other vinylindoles and other dienophiles (ethyl acrylate, cinnamaldehyde); Product distribution;
参考文献
Kusurkar, R. S.; Patil, U. G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 1038 - 1041
