N-(4-氯苯亚甲基)-4-甲苯磺酰胺合成路线 （共 24 条）
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2; potassium tert-butylate; 1,3-bis-(1-adamantyl)imidazolium chloride in tetrahydrofuran; 1,4-dioxane T=70°C; 6 h; Inert atmosphere;
参考文献
Md., Abu Bakar; Suzuki, Yumiko; Sato, Masayuki
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 7 p. 973 - 976
反应条件
[Rh(NCMe)2(cod)][BF4] in tetrahydrofuran T=60°C; Phenylation; 20 h;
参考文献
Oi, Shuichi; Moro, Mitsutoshi; Fukuhara, Hiroe; Kawanishi, Takanori; Inoue, Yoshio
Tetrahedron Letters, 1999 , vol. 40, # 52 p. 9259 - 9262
反应条件
1: PhH*Cr(CO)3 With n-butyllithium in tetrahydrofuran; hexane T=-35°C; 0.5 h; 2: N-(p-chlorobenziylidene)-4-methylbenzenesulfonamide in tetrahydrofuran; hexane T=-35°C; 5 h; 3: With air in dichloromethane T=20°C; 12 h; sunlight exposition;
参考文献
Chen, Yong-Jun; Zhao, Cui-Hua; Liu, Li; Wang, Dong
Journal of Chemical Research - Part S, 2003 , # 11 p. 740 - 743
反应条件
1: With [2,2']bipyridinyl; sodium acetate; copper(l) chloride in 4-methyl-chlorobenzene; toluene T=180°C; 0.5 h; Microwave irradiation; 2: With hydrogenchloride in 4-methyl-chlorobenzene; water; toluene
参考文献
Liao, Yuan-Xi; Hu, Qiao-Sheng
Journal of Organic Chemistry, 2011 , vol. 76, # 18 p. 7602 - 7607
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2; potassium tert-butylate; triphenylphosphine in tetrahydrofuran T=40°C; 15 h; Molecular sieve; optical yield given as percent de;
参考文献
Ahlsten, Nanna; Martin-Matute, Belen
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 16 p. 2657 - 2666
反应条件
1: CH2=CHCH2PPh3(1+)*Br(1-) in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: N-(p-chlorobenziylidene)-4-methylbenzenesulfonamide in tetrahydrofuran; hexane T=-78 - 20°C; 12 h; Inert atmosphere; optical yield given as percent destereoselective reaction;
参考文献
Dong, De-Jun; Li, Hai-Hua; Tian, Shi-Kai
Journal of the American Chemical Society, 2010 , vol. 132, # 14 p. 5018 - 5020
反应条件
1: 76 percent / 2.5M BuLi / hexane; tetrahydrofuran / 4 h / -78 °C
2: 47 percent / NaOH / ethanol / 12 h / 90 °C
View Scheme
参考文献
Katritzky; Li; Gordeev
Synthesis, 1994 , # 1 p. 93 - 96
反应条件
1-acetyl-2,3-dimethylimidazolidine in methanol; acetonitrile
5 h; Heating;
参考文献
Li, Donghong; Zhang, Yongbin; Zhou, Guofu; Guo, Wei
Synlett, 2008 , # 2 p. 225 - 228
反应条件
hydrogenchloride; samarium in tetrahydrofuran
T=20°C; Title compound not separated from byproducts;
参考文献
Liu, Xi; Liu, Yunkui; Zhang, Yongmin
Tetrahedron Letters, 2002 , vol. 43, # 38 p. 6787 - 6789
反应条件
1.1: sodium tetrahydroborate / methanol / 2 h / 20 °C
2.1: sodium hydride / dichloromethane / 0.33 h
2.2: 2 h
View Scheme
参考文献
Li, Man-Bo; Tang, Xiang-Ling; Tian, Shi-Kai
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1980 - 1984
