1: 68 percent / tetrahydrofuran / -20 - 20 °C 2: 75 percent / 2N KOH / 2 h / Heating 3: 53 percent / Et3SiH / trifluoroacetic acid / 24 h / 45 °C 4: 47 percent / BBr3 / CH2Cl2 / -20 - 20 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
1: 1.) lithium / 1.) ether, 2 h 2: decarboxylation 3: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
1: 78 percent / hydrazine hydrate / 2 h / Heating 2: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C 3: 93 percent / toluene / 2.5 h / Heating 4: 8.7 g / sodium hydroxide (20percent) / 60 °C 8: 28.8 g / fluoroboric acid, sodium nitrite / H2O 9: 7.6 g / warming, distillation 10: 1.) lithium / 1.) ether, 2 h 11: decarboxylation 12: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
1: 84 percent / sodium hydroxide / heating 5: 28.8 g / fluoroboric acid, sodium nitrite / H2O 6: 7.6 g / warming, distillation 7: 1.) lithium / 1.) ether, 2 h 8: decarboxylation 9: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
