N-苄氧羰基-L-异亮氨酸合成路线 （共 29 条）
反应条件
sodium hydroxide in 1,4-dioxane; toluene T=0°C;
参考文献
Wipf, Peter; Heimgartner, Heinz
Helvetica Chimica Acta, 1988 , vol. 71, p. 140 - 154
反应条件
triethylamine in water; N,N-dimethyl-formamide 0.5 h; Ambient temperature;
参考文献
Kim, Sunggak; Lee, Jae In; Yi, Kyu Yang
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 12 p. 3570 - 3575
反应条件
triethylamine in water; N,N-dimethyl-formamide 0.5 h; Ambient temperature;
参考文献
Kim, Sunggak; Lee, Jae In; Yi, Kyu Yang
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 12 p. 3570 - 3575
反应条件
triethylamine in water Ambient temperature;
参考文献
Azuse; Tamura; Kinomura; Okai; Kouge; Hamatsu; Koizumi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3103 - 3108
反应条件
sodium chloride; calcium chloride; papain in N,N-dimethyl-formamide T=25°C; pH=8; 1.5 h; aq. bufferEnzymatic reaction;
参考文献
ChemBioChem, , vol. 12, # 14 p. 2201 - 2207
反应条件
1: 90 percent / Et3N / acetonitrile / 2 h / 5 °C 2: 85 percent / Et3N / H2O / Ambient temperature View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3103 - 3108
反应条件
1.1: 90 percent / benzaldehyde; glacial acetic acid / 2 h / 100 °C 2.1: p-TsOH*H2O / toluene / 18 h / Heating 2.2: K2CO3 / H2O; ethyl acetate / pH 8.5 3.1: 96 percent / NaHCO3 / H2O / 0.75 h / 5 - 10 °C 4.1: alcalase; NaOH / H2O / 28 h / 39 °C / pH 7.8 / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 14, # 20 p. 3189 - 3196
反应条件
toluene-4-sulfonic acid; threo-1,4-dimercapto-2,3-butanediol; papain in N,N-dimethyl-formamide pH=8; 6 h; aq. buffer;
参考文献
ChemBioChem, , vol. 13, # 9 p. 1319 - 1326
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide; Dec-L-His in acetonitrile T=25°C; 0.02M phosphate buffer, pH=7.3; other catalysts; Rate constant;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 607 - 612
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4585 - 4592
