2-(4-溴丁氧基)四氢-2H-吡喃合成路线 （共 24 条）
反应条件
1: 56 percent / Li2CuCl4 / tetrahydrofuran / 3 h / -10 °C
2: 52 percent / pyridinium p-toluenesulfonate / methanol / 6 h / 55 °C
3: 60 percent / pyridinium dichromate / CH2Cl2 / 24 h
View Scheme
参考文献
Trehan; Vig; Singh; Sharma; Kad
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 6 p. 518 - 520
反应条件
hydrogenchloride
1) liq. NH3, ether, 8 h, reflux, 2) methanol, 4 h, RT; Yield given. Multistep reaction;
参考文献
Robinson, John A.; Flohr, Helmut; Kempe, Uwe Max; Pannhorst, Wolfgang; Retey, Janos
Liebigs Annalen der Chemie, 1983 , # 2 p. 181 - 203
反应条件
(i) liq. NH3, (ii) /BRN= 1422220/, Et2O; Multistep reaction;
参考文献
Flohr,H. et al.
Helvetica Chimica Acta, 1978 , vol. 61, p. 1565 - 1587
反应条件
lithium amide
hexamethylphosphoroamide, 1.) 1h, room temperature, 2.) 10 h, 30 deg C; Yield given. Multistep reaction;
参考文献
Kovalev, B. G.; Matveeva, E. D.; Stan, V. V.; Vovk, G. A.; Yudin, L. G.; Kost, A. N.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 10 p. 1728 - 1733
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 10 p. 2032 - 2038
