1: 47.5 percent / acetonitrile / 20 °C 2: 47.6 percent / xylene / 0.75 h / 140 °C View Scheme

1: 1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione With pyridine; palladium diacetate; copper (II) acetate monohydrate; copper(l) chloride in N,N-dimethyl acetamide T=20°C; Heck reaction; 0.0833333 h; Inert atmosphere; 2: 1,2-dimethoxy-4-ethenyl-benzene in N,N-dimethyl acetamide T=120°C; Heck reaction; 20 h; Inert atmosphere;