potassium fluoride in methanol desilylation; amide cleavage;

1: 70 percent / K2CO3; Pd(PPh3)4 / acetonitrile / 45 °C 2: AlCl3; 2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl bromide View Scheme

1: 1-iodo-1-(3,4,5-trimethoxyphenyl)ethylene With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene in water; N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 0.0333333 h; 2: 2-(trimethylsilylethynyl)trifluoroacetanilide in water; N,N-dimethyl-formamide T=20°C; 12 h;