3-(2-硝基乙基)吲哚合成路线 (共 23 条)
反应条件
ethanol; sodium ethanolate
参考文献
Henry; Leete
Journal of the American Chemical Society, 1957 , vol. 79, p. 5254
参考文献
Noland; Hartman
Journal of the American Chemical Society, 1954 , vol. 76, p. 3227
反应条件
in xylene T=90 - 100°C; 5 h;
参考文献
Black, David St. C.; Craig, Donald C.; Deb-Das, Renu B.; Kumar, Naresh; Wright, Timothy A.
Australian Journal of Chemistry, 1993 , vol. 46, # 11 p. 1725 - 1742
反应条件
sodium methylate; dimethyl sulfate in methanol
参考文献
Hermkens, Pedro H. H.; Maarseveen, Jan H. v.; Ottenheijm, Harry C. J.; Kruse, Chris G.; Scheeren, Hans W.
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 3998 - 4006
反应条件
Na[HB(OMe)3] in tetrahydrofuran 0.333333 h; pH=6; Yields of byproduct given;
参考文献
Kruse, Lawrence I.; Hilbert, Eileen L.
Heterocycles, 1983 , vol. 20, # 7 p. 1373 - 1377
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 1 h; Ambient temperature; Yield given;
参考文献
Iwao, Masatomo; Motoi, Osamu
Tetrahedron Letters, 1995 , vol. 36, # 33 p. 5929 - 5932
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran Ambient temperature1.1 equiv. nitromethane; Yield given. Yields of byproduct given;
参考文献
Iwao, Masatomo; Motoi, Osamu
Tetrahedron Letters, 1995 , vol. 36, # 33 p. 5929 - 5932
反应条件
1: acetic acid 2: sodium tetrahydroborate; silica gel / chloroform; isopropyl alcohol View Scheme
参考文献
Burkhard, Johannes A.; Tchitchanov, Boris H.; Carreira, Erick M.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 23 p. 5379 - 5382
参考文献
Henry; Leete
Journal of the American Chemical Society, 1957 , vol. 79, p. 5254
反应条件
1: hydrogen; palladium 10 on activated carbon / 12 h / 40 °C 2: triethylamine / dichloromethane / 3 h / 20 °C View Scheme
参考文献
Guo, Xiaoke; Yang, Qian; Xu, Jing; Zhang, Li; Chu, Hongxi; Yu, Peng; Zhu, Yingying; Wei, Jinglian; Chen, Weilin; Zhang, Yaozhong; Zhang, Xiaojin; Sun, Haopeng; Tang, Yiqun; You, Qidong
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6466 - 6476