317365-33-6合成路线

参考文献

Clark, Roger B.; Elbaum, Daniel
Tetrahedron, 2007 , vol. 63, # 14 p. 3057 - 3065

3022-15-9哌嗪-2-羧酸二盐酸盐+

501-53-1氯甲酸苄酯

317365-33-6+

161894-56-0

参考文献

CRITICAL THERAPEUTICS, INC.
Patent: WO2007/146066 A2, 2007 ;
Location in patent: Page/Page column 192-193 ;

317365-33-6

参考文献

Merck and Co., Inc.
Patent: US6498165 B1, 2002 ;
US 6498165 B1

2762-32-5哌嗪-2-甲酸

317365-33-6

参考文献

Merck and Co., Inc.
Patent: US6316444 B1, 2001 ;
US 6316444 B1

301673-16-51-BOC-3-羟甲基哌嗪+

501-53-1氯甲酸苄酯

317365-33-6

参考文献

CRITICAL THERAPEUTICS, INC.
Patent: WO2007/146066 A2, 2007 ;
Location in patent: Page/Page column 83 ;

935544-47-13-氧代四氢-1H-噁唑并[3,4-a]吡嗪-7(3H)-羧酸叔丁酯+

100-51-6苯甲醇

参考文献

Clark, Roger B.; Elbaum, Daniel
Tetrahedron, 2007 , vol. 63, # 14 p. 3057 - 3065

24424-99-5二碳酸二叔丁酯

317365-33-6

参考文献

Clark, Roger B.; Elbaum, Daniel
Tetrahedron, 2007 , vol. 63, # 14 p. 3057 - 3065

143540-05-02-(羟甲基)-1,4-哌嗪二羧酸二叔丁酯

317365-33-6

参考文献

Clark, Roger B.; Elbaum, Daniel
Tetrahedron, 2007 , vol. 63, # 14 p. 3057 - 3065

181955-79-31,4-双(N-Boc)哌嗪-2-甲酸

317365-33-6

参考文献

Clark, Roger B.; Elbaum, Daniel
Tetrahedron, 2007 , vol. 63, # 14 p. 3057 - 3065

126937-42-6(+/-)-1-苄氧羰基-4-Boc-哌嗪-2-羧酸甲酯

317365-33-6

参考文献

Hunt, Julianne A.; Beresis, Richard T.; Goulet, Joung L.; Holmes, Mark A.; Hong, Xinfang J.; Kovacs, Ernest; Mills, Sander G.; Ruzek, Rowena D.; Wong, Frederick; Hermes, Jeffrey D.; Park, Young-Whan; Salowe, Scott P.; Sonatore, Lisa M.; Wu, Lin; Woods, Andrea; Zaller, Dennis M.; Sinclair, Peter J.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 18 p. 5440 - 5443