(3aR,4R,5R,6aS)-六氢-2-氧代-4-[(1E)-3-氧代-1-辛烯基]-2H-环戊并[b]呋喃-5-基 [1,1’-联苯]-4-甲酸酯合成路线 （共 7 条）
参考文献
K.K. Ueno Seiyaku Oyo Kenkyujo
Patent: US5117042 A1, 1992 ;
反应条件
sodium hydride in ethylene glycol dimethyl ether T=0 - 20°C; Yield given;
参考文献
Chen, Lian-yong; Ghosez, Leon
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1181 - 1184
反应条件
1: pyridine / Ambient temperature 2: 1.) O3, 2.) Me2S / 1.) CH3OH, CH2Cl2, -78 deg C 3: NaH / 1,2-dimethoxy-ethane / 0 - 20 °C View Scheme
参考文献
Chen, Lian-yong; Ghosez, Leon
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1181 - 1184
反应条件
1: NaBH4 / methanol / 0 °C 2: pyridine / Ambient temperature 3: 1.) O3, 2.) Me2S / 1.) CH3OH, CH2Cl2, -78 deg C 4: NaH / 1,2-dimethoxy-ethane / 0 - 20 °C View Scheme
参考文献
Chen, Lian-yong; Ghosez, Leon
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1181 - 1184
反应条件
1: 1.) O3, 2.) Me2S / 1.) CH3OH, CH2Cl2, -78 deg C 2: NaH / 1,2-dimethoxy-ethane / 0 - 20 °C View Scheme
参考文献
Chen, Lian-yong; Ghosez, Leon
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1181 - 1184
反应条件
1: n-Bu4NF / tetrahydrofuran 2: Dess-Martin reagent / CH2Cl2 / Ambient temperature 3: NaBH4 / methanol / 0 °C 4: pyridine / Ambient temperature 5: 1.) O3, 2.) Me2S / 1.) CH3OH, CH2Cl2, -78 deg C 6: NaH / 1,2-dimethoxy-ethane / 0 - 20 °C View Scheme
参考文献
Chen, Lian-yong; Ghosez, Leon
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1181 - 1184
反应条件
1: diisobutylaluminium 2,6-t-butyl-4-methylphenyl / toluene / 2.5 h / -78 - -10 °C 2: K2CO3, MeOH / 2 h / 25 °C View Scheme
参考文献
Iguchi; Nakai; Hayashi; et al.
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3033 - 3041
