2-苄基-1,2,3,4-四氢-6,7-二甲氧基异喹啉合成路线 （共 12 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; De Grazia, Sara; Di Giorgio, Rosa Maria; Festa, Filomena; De Luca, Grazia
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 1 p. 54 - 62
反应条件
1: 1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline hydrochloride With triethylamine in ethanol T=20°C; 1 h; Inert atmosphere; 2: benzyl bromide in ethanol T=20°C; 3.5 h; Inert atmosphere;
参考文献
Luethy, Monique; Darmency, Vincent; Renaud, Philippe
European Journal of Organic Chemistry, 2011 , # 3 p. 547 - 552
反应条件
tri-n-butyl-tin hydride in methanol 5 h; Ambient temperature;
参考文献
Palmisano, Giovanni; Lesma Giordano; Nali, Micaela; Rindone, Bruno; Tollari, Stefano
Synthesis, 1985 , # 11 p. 1072 - 1074
反应条件
FeCl3·6H2O in nitrobenzene T=120°C; 10 h;
参考文献
Zhang, Jing; Zhang, Ao
Chemistry - A European Journal, 2009 , vol. 15, # 42 p. 11119 - 11122
反应条件
1: NaBH4 / methanol 2: 1.) H(1+), 2.) HCl / 2.) EtOH View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
1: LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 2: benzene / Heating 3: NaBH4 / ethanol / 0.5 h / Ambient temperature 4: K2CO3 / Ambient temperature 5: trifluoroacetic acid / 1 h / Ambient temperature View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
1: ammonium acetate / 3 h / Heating 2: LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 3: benzene / Heating 4: NaBH4 / ethanol / 0.5 h / Ambient temperature 5: K2CO3 / Ambient temperature 6: trifluoroacetic acid / 1 h / Ambient temperature View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
1: benzene / Heating 2: NaBH4 / ethanol / 0.5 h / Ambient temperature 3: K2CO3 / Ambient temperature 4: trifluoroacetic acid / 1 h / Ambient temperature View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
反应条件
hydrogenchloride in methanol 4 h; Heating;
参考文献
Vinogradova, V. I.; Golodnyuk, T. I.; Yunusov, M. S.; Suleimanova, G. A.; Tulyaganov, N.
Chemistry of Natural Compounds, 1993 , vol. 29, # 5 p. 654 - 657
Khimiya Prirodnykh Soedinenii, 1993 , # 5 p. 736 - 740
反应条件
trifluoroacetic acid 1 h; Ambient temperature; Yield given;
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
