2-氨基-3-甲氧基苯甲酸合成路线 (共 68 条)
反应条件
2: 1) 3N HCl, 2) 50percent aq. NaOH, methanol / 1) 100 deg C, 20 min, 2) reflux, 30 min View Scheme
参考文献
Tetrahedron, , vol. 47, # 27 p. 5051 - 5070
参考文献
Bulletin de la Societe Chimique de France, , p. 782,785
反应条件
1: alkali 2: nitric acid / <60 3: tin; hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 101, p. 548
反应条件
1: nitric acid / <60 2: tin; hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 101, p. 548
反应条件
1: Ozonolyse 2: aqueous HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 782,785
参考文献
Journal of Physical Chemistry, , vol. 63, p. 1457,1460
反应条件
hydrogenchloride; ammonium hydroxide; sodium hydroxide; hydroxylamine hydrochloride; copper(II) sulfate; sodium nitrite Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Costero, Ana M.; Pitarch, Miguel
Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 2939 - 2944
反应条件
hydrogenchloride; ammonium hydroxide; sodium disulfite; iron(III) chloride; copper(II) sulfate; sodium nitrite Multistep reaction. Title compound not separated from byproducts;
参考文献
Costero, Ana M.; Pitarch, Miguel
Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 2939 - 2944
反应条件
in tetrahydrofuran 3 h; RefluxInert atmosphere;
参考文献
WO2011/35124 A1, ;
Page/Page column 83 ;
WO 2011/035124 A1
反应条件
in 1,4-dioxane; benzene Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 6 p. 735 - 742