1-(3-甲氧苯基)-2-硝基乙烯合成路线 （共 13 条）
反应条件
ammonium acetate; acetic acid T=100°C; 12 h;
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 0 - 80 °C 2: hydrogenchloride / water / 1 h / 60 °C 3: hydrogenchloride / isopropyl alcohol; water / 18 h / 20 °C 4: sodium hydrogencarbonate / water / 0.5 h / 20 °C View Scheme
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
Amberlyst A-26 (OH-); dihydrogen peroxide in 1,4-dioxane T=20°C; 12 h;
参考文献
Lakouraj, Moslem M.; Movassagh, Barahman; Bahrami, Kyumars
Monatshefte fur Chemie, 2002 , vol. 133, # 9 p. 1193 - 1196
反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 0 - 80 °C 2.1: hydrogenchloride / water / 1 h / 60 °C 3.1: hydrogenchloride / isopropyl alcohol; water / 18 h / 20 °C 4.1: hydrogen bromide; water / 5 h / |Reflux 5.1: triethylamine / tetrahydrofuran; water 6.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h / 0 - 20 °C 6.2: 1 h 7.1: hydrogenchloride / water; ethanol / 6 h / 20 °C View Scheme
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 0 - 80 °C 2: hydrogenchloride / water / 1 h / 60 °C 3: hydrogenchloride / isopropyl alcohol; water / 18 h / 20 °C View Scheme
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 0 - 80 °C 2: hydrogenchloride / water / 1 h / 60 °C 3: hydrogenchloride / isopropyl alcohol; water / 18 h / 20 °C 4: hydrogen bromide; water / 5 h / |Reflux View Scheme
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 0 - 80 °C 2: hydrogenchloride / water / 1 h / 60 °C 3: hydrogenchloride / isopropyl alcohol; water / 18 h / 20 °C 4: hydrogen bromide; water / 5 h / |Reflux 5: triethylamine / tetrahydrofuran; water View Scheme
参考文献
Yang, Su Hui; Song, Chin-Hee; Van, Hue Thi My; Park, Eunsook; Khadka, Daulat Bikram; Gong, Eun-Yeung; Lee, Keesook; Cho, Won-Jea
Journal of Medicinal Chemistry, 2013 , vol. 56, # 8 p. 3414 - 3418
反应条件
hydrogen; carbon palladium T=85°C; P=37503 Torr;
参考文献
European Journal of Medicinal Chemistry, , vol. 18, # 4 p. 319 - 329
反应条件
1: 75 percent / LiAlH4 / diethyl ether / 1.5 h / Heating 2: 73 percent / pyridine / 2 h / Ambient temperature View Scheme
参考文献
Chinnasamy, Pennamuthiriar; Iwasa, Kinuko; Angerer, Silvia von; Weimar, Christian; Wiegrebe, Wolfgang
Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 9 p. 790 - 798
反应条件
1: 76 percent / cuprous iodide / tetrahydrofuran; diethyl ether / 1.5 h / 0 °C
2: ammonium formate / 10percent palladium-charcoal / methanol / 10 h / Ambient temperature
3: 1 h / Ambient temperature
4: 100 percent / phosphorus oxychloride / toluene / 20 h / Heating
5: 70 percent / diphenyl disulphide / 1,2,3,4-tetrahydro-naphthalene / 20 h / 200 °C
View Scheme
参考文献
Martinez, Silvio J.; Larsen, Lesley; Street, Janathan D.; Joule, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1705 - 1710
