3-巯基-1,2,4-三氮唑合成路线 （共 17 条）
反应条件
in chloroform 0.25 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 4 p. 359 - 368
反应条件
sodium periodate in water T=20°C; 0.0333333 h;
参考文献
Monsanto Technology LLC
Patent: US6461997 B1, 2002 ;
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Abramova, N. D.; Skvortsova, G. G.; Trzhtsinskaya, B. V.
Journal of Organic Chemistry USSR (English Translation), 1984 , p. 1854
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 9 p. 2031 - 2032
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 42, # 3 p. 314 - 318
European Journal of Medicinal Chemistry, , vol. 27, # 4 p. 359 - 368
反应条件
1: 2-mercapto-1H-1,3,4-triazole With sodium in methanol; ethylene glycol dimethyl ether T=20°C; 0.166667 h; 2: p-methoxybenzyl chloride in methanol; ethylene glycol dimethyl ether T=20 - 50°C; 5.41667 h;
参考文献
Klimesova, Vera; Zahajska, Lenka; Waisser, Karel; Kaustova, Jarmila; Moellmann, Ute
Farmaco, 2004 , vol. 59, # 4 p. 279 - 288
反应条件
sodium hydroxide
2) EtOH, a) 6 h, b) reflux, 5 h; Yield given. Multistep reaction;
参考文献
Lagorce; Moulard; Raby
Arzneimittel-Forschung/Drug Research, 1992 , vol. 42, # 3 p. 314 - 318
反应条件
Cadmium acetate in 1,4-dioxane
T=180°C; P=12160 Torr; 2 h; other 1,2,4-triazoles;
参考文献
Trzhtsinskaya, B. V.; Apakina, E. V.; Afonin, A. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.2 p. 834 - 836
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 928 - 931
