4-羟基-6-氟喹啉-3-甲酸乙酯合成路线 （共 8 条）
参考文献
Eswaran, Sumesh; Adhikari, Airody Vasudeva; Pal, Nishith K.; Chowdhury, Imran H.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1040 - 1044
反应条件
1: pyridine / toluene / 2 h / Heating 2: diphenyl ether / 1 h / 250 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6351 - 6363
反应条件
1: pyridine / toluene / 2 h / Heating 2: diphenyl ether / 1 h / 250 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6351 - 6363
反应条件
1: T=140°C; 1 h; Inert atmosphere; 2: in diphenylether 2 h; RefluxInert atmosphere;
参考文献
Goncalves, Victor; Brannigan, James A.; Whalley, David; Ansell, Keith H.; Saxty, Barbara; Holder, Anthony A.; Wilkinson, Anthony J.; Tate, Edward W.; Leatherbarrow, Robin J.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3578 - 3582
参考文献
Journal of the American Chemical Society, , vol. 69, p. 371,373
反应条件
1: aqueous NaOH 2: diphenyl ether; biphenyl View Scheme
参考文献
Snyder et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 371,373
反应条件
1: With trichlorophosphate T=100°C; 0.5 h; 2: With ammonia in water T=0°C;
参考文献
BIOLIPOX AB
Patent: WO2007/51982 A1, 2007 ;
Location in patent: Page/Page column 43-44 ;
反应条件
1: aqueous NaOH 2: diphenyl ether; biphenyl 3: phosphorus (V)-chloride; phosphoryl chloride / 130 °C View Scheme
参考文献
Snyder et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 371,373
