5-甲基-1-[3,4,5-三羟基-6-(羟基甲基)四氢吡喃-2-基]嘧啶-2,4-二酮合成路线 （共 6 条）
反应条件
sodium methylate in methanol 2 h; Ambient temperature;
参考文献
Leclerq, Francoise; Antonakis, Kostas
Carbohydrate Research, 1991 , vol. 222, p. 277 - 282
反应条件
hydrogen fluoride in acetonitrile 8.5 h; Ambient temperature;
参考文献
Chow, Ken; Danishefsky, Samuel
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4211 - 4214
反应条件
1: 1.) hexamethyldisilazane, 2.) SnCl4 / 1.) pyridine, reflux, 6 h, 2.) 1,2-dichloroethane, 20 deg C, 16 h 2: 87 percent / NH3 / methanol / 20 h / 20 °C View Scheme
参考文献
Leclerq, Francoise; Antonakis, Kostas
Carbohydrate Research, 1991 , vol. 222, p. 277 - 282
反应条件
2: methanol. HCl View Scheme
参考文献
Young et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 2126,2128
反应条件
1: 1.) hexamethyldisilazane, 2.) SnCl4 / 1.) pyridine, reflux, 6 h, 2.) 1,2-dichloroethane, 20 deg C, 16 h 2: 87 percent / NH3 / methanol / 20 h / 20 °C View Scheme
参考文献
Huchting, Johanna; Meier, Chris
European Journal of Organic Chemistry, 2014 , vol. 2014, # 16 p. 3423 - 3429
反应条件
anschliessende Hydrolyse mit methanol.HCl;
参考文献
Visser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 1926
