反应条件
1: 2.) 48percent HBr / 1.) acetone, reflux, 12 h, 2.) MeOH, reflux, 2 h
2: 72 percent / dimethylformamide / 48 h / Heating
View Scheme
参考文献
Sundberg, Richard J.; Biswas, Sujay; Murthi, Krishna Kumar; Rowe, Donna; McCall, John W.; Dzimianski, Michael T.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 22 p. 4317 - 4328