2,4-二羟基-6-甲基苯甲酸甲酯合成路线 (共 72 条)
参考文献
Stenhouse
Justus Liebigs Annalen der Chemie, 1863 , vol. 125, p. 359
Justus Liebigs Annalen der Chemie, 1869 , vol. 149, p. 293
反应条件
potassium carbonate in acetone 24 h; Heating;
参考文献
Pulgarin, Cesar; Gunzinger, Jan; Tabacchi, Raffaele
Helvetica Chimica Acta, 1985 , vol. 68, p. 1948 - 1951
反应条件
potassium carbonate; dimethyl sulfate in diethyl ether; acetone
参考文献
Aventis Pharma S.A.
Patent: EP1300403 A1, 2003 ;
反应条件
potassium carbonate 12 h; Heating;
参考文献
Hashimoto, Toshihiro; Asakawa, Yoshinori
Heterocycles, 1998 , vol. 47, # 2 p. 1067 - 1110
反应条件
in diethyl ether T=0 - 5°C; 168 h;
参考文献
Jones, Graham B.; Huber, Robert S.; Chapman, Brant J.
Tetrahedron Asymmetry, 1997 , vol. 8, # 11 p. 1797 - 1809
反应条件
2: Raney nickel; ethanol 3: aqueous NaOH View Scheme
参考文献
Aghoramurthy et al.
Chemistry and Industry (London, United Kingdom), 1954 , p. 1327
反应条件
1: 29.8 g / SO2Cl2 / CH2Cl2 / 2.75 h / Heating 2: 14.3 g / NaOH (aq) / 3.5 h / Heating View Scheme
参考文献
Sala, Tony; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 855 - 869
反应条件
2: Raney nickel; ethanol View Scheme
参考文献
Aghoramurthy et al.
Chemistry and Industry (London, United Kingdom), 1954 , p. 1327
反应条件
hydrogenchloride; aluminium trichloride; zinc cyanide in diethyl ether 18 h; Ambient temperature;
参考文献
Pulgarin, Cesar; Tabacchi, Raffaele
Helvetica Chimica Acta, 1989 , vol. 72, p. 1061 - 1065
反应条件
aluminium trichloride in diethyl ether Formylation; Gattermann formylation;
参考文献
Ponde, Datta E.; Ramalingam; Patil, Mahesh L.; Borate, Hanumant B.; Deshpande, Vishnu H.
Tetrahedron Letters, 1999 , vol. 40, # 29 p. 5399 - 5400