2-甲基四氢呋喃-3-酮合成路线 （共 12 条）
反应条件
hydrogenchloride; hydrogen sulfide; sodium hydrogencarbonate in diethyl ether; diethylene glycol dimethyl ether; water
参考文献
International Flavors and Fragrances Inc.
Patent: US4020175 A1, 1977 ;
反应条件
1.1: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / ethanol; tetrahydrofuran / 3.5 h / -80 - 20 °C / |Inert atmosphere
1.2: 1 h / -60 °C
2.1: lithium bromide; lithium carbonate / ethyl acetate / 0.08 h / 180 °C
View Scheme
参考文献
Winkler, Christoph K.; Clay, Dorina; Entner, Marcello; Plank, Markus; Faber, Kurt
Chemistry - A European Journal, 2014 , vol. 20, # 5 p. 1403 - 1409
